![]() Every three days the sugar utilization analysis was carried out and found that the growth of organism increased with the decrease of sugar. The average OD value was calculated and compared with the standard curve to obtain the concentration of dextrose in the production media. The OD of the sample from the dextrose media sample was read at 540 nm and tabulated in Table 3. The standard curve for the different concentrations of dextrose, maltose, and lactose was drawn based on the optical density (OD) value ( Table 2). The sugar utilization in the culture media was quantified based on DNS method, which showed that the organism utilized the sugar as carbon source for their growth. Results of this study suggest that soil and citrus fruit samples seem to be good source of Penicillium species. The expected outcome of this work is to explore antibiotics for the upcoming threat by the mutant pathogens. chrysogenum) from various soil and citrus sources. This present investigation was aimed to explore the mycoflora diversity of antibiotics producing Penicillium chrysogenum ( P. Accordingly, new studies that examine China's economic trends, investment environment, industry development, supply and demand, industry capacity, industry structure, marketing channels and major industry participants regarding historical data and long-term forecasts through 20 are presented. In the next five years, both production and demand will continue to grow. Īccording to the recent research done by “”, China's demand for penicillin has grown at a fast pace in the past decade. ![]() It is estimated that there are 1.5 million fungal species on earth, of which only about 70 000 have been described till recently. They perform ecological services that strongly impact the quality of human life and have enormous potential for providing economic benefits, e.g., the isolation and identification of the soil fungus Penicillium leading to a large pharmaceutical industry of antibiotics. The role of fungi in the soil is an extremely complex and is fundamental to the soil ecosystem. ![]() Therefore, there was a considerable change in quantity of the penicillin produced from both the samples.įungi are an important component of the soil microbiota typically constituting more of the soil biomass than bacteria, depending on soil depth and nutrient conditions. ![]() Accordingly, the penicillin produced from the soil sample of Government General Hospital had the high milli absorbance unit of 441.5 mAu compared with that of the penicillin produced from Sanjay Gandhi Hospital sample, 85.52 mAu. HPLC data provided the analytical and confirmation details of the penicillin produced. Characterization of penicillin on pathogens, like wild Escherichia coli strain, Klebsiella spp., and MRSA, gave quite interesting results such as no activity on the later strain as it is resistant. Optimum production of penicillin was obtained in maltose which proved maximum zone of inhibition during assay. ![]() Different production media showed varied range of growth of Penicillium. From the various soil and citrus samples used for analysis, only the soil sample from Government General Hospital of Bangalore, India, and Sanjay Gandhi Hospital, Bangalore, India, showed some potential growth of the desired fungi P. ![]()
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